File:Loratadine.svg · Wikimedia Commons · See Wikimedia Commons
loratadine
Sign in to saveLoratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. It is taken orally.
Key facts
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 408580634
- Drug.image
- Loratadine.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Loratadine - 3d, portrait orientation.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Claritin, Claratyne, Clarityn, others
- Drug.MedlinePlus
- a697038
- Drug.DailyMedID
- Loratadine
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth
- Drug.class
- Second-generation antihistamine
- Drug.ATC_prefix
- R06
- Drug.ATC_suffix
- AX13
- Drug.legal_AU
- OTC
- Drug.legal_CA
- OTC
- Drug.legal_UK
- GSL
- Drug.legal_UK_comment
- / Pharmacy
via Wikipedia infobox
Chemical data
- Formula
- C22H23ClN2O2
- Molecular weight
- 382.9 g/mol
- IUPAC name
- ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
- SMILES
- CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
- InChIKey
- JCCNYMKQOSZNPW-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 42.4 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 382.144806
Show 5 more facts
- chemical formula
- C₂₂H₂₃ClN₂O₂
- defined daily dose
- 5
- Commons category
- Loratadine
- World Health Organisation international non-proprietary name
- loratadine
- canonical SMILES
- CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
Sources (7)
via Wikidata · CC0
~10 min read
Article
15 sectionsContents
- Medical uses
- Combination drugs
- Dosage forms
- Contraindications
- Adverse effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- History
- Society and culture
- Over the counter
- Brands
- Marketing
- References
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. It is taken orally.
Common side effects include sleepiness, dry mouth, and headache. Serious side effects are rare and include allergic reactions, seizures, and liver problems. Use during pregnancy appears to be safe but has not been well studied. It is not recommended in children less than two years old. It is in the second-generation antihistamine family of medications.