fosaprepitant

Also known as Ivemend®, MK-0517, L-758,298, L-758298, Fosaprepitantum

Fosaprepitant, sold under the brand names Emend (US) and Ivemend (EU) among others, is an antiemetic medication, administered intravenously. It is a prodrug of aprepitant.

Research

269 papers

Fosaprepitant for postoperative nausea and vomiting in patients undergoing laparoscopic gastrointestinal surgery: a randomised trial.British journal of anaesthesia · 2023
Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review.Cancer chemotherapy and pharmacology · 2022
The clinical research study for fosaprepitant to prevent chemotherapy-induced nausea and vomiting: A review.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2023
Fosaprepitant Dimeglumine: A Review in the Prevention of Nausea and Vomiting Associated with Chemotherapy.Drugs · 2016
Aprepitant and fosaprepitant drug interactions: a systematic review.British journal of clinical pharmacology · 2017

via PubMed

Wikidata facts

Mass: 614.117

Show 5 more facts

chemical formula: C₂₃H₂₂F₇N₄O₆P
Commons category: Fosaprepitant
canonical SMILES: CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F
isomeric SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F
World Health Organisation international non-proprietary name: fosaprepitant

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