GBF1
Sign in to saveAlso known as ARF1GEF, golgi brefeldin A resistant guanine nucleotide exchange factor 1, CMT2GG
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.
Gene data
GBF1- Name
- golgi brefeldin A resistant guanine nucleotide exchange factor 1
- Type
- protein-coding
- Aliases
- ARF1GEF, CMT2GG, CMTDI2, CMTDIA
This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010].
via MyGene.info
Gene · Ensembl
golgi brefeldin A resistant guanine nucleotide exchange factor 1
- Symbol
- GBF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:102,245,371-102,382,899
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 37897
- exact match
- identifiers.org/ncbigene/8729
- genomic end
- 104142656
- genomic start
- 102245371
- cytogenetic location
- 10q24.32
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the GBF1 gene.
==References==