guanabenz
Also known as GBZ, NSC 68982, Wy 8678, Wytensin®, Guanabenzo, Guanabenzum
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist that is selective to the alpha-2 adrenergic receptor. Guanabenz is used as an antihypertensive drug used in the treatment of high blood pressure (hypertension).
Chemical data
- Formula
- C8H8Cl2N4
- Molecular weight
- 231.08 g/mol
- IUPAC name
- 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine
via PubChem
Research
686 papers- Guanabenz.2006
- Guanabenz. A review of its pharmacodynamic properties and therapeutic efficacy in hypertension.Drugs · 1983
- Guanabenz ameliorates disease in vanishing white matter mice in contrast to sephin1.Annals of clinical and translational neurology · 2022
- Guanabenz modulates microglia and macrophages during demyelination.Scientific reports · 2020
- Guanabenz and Clonidine, α2-Adrenergic Receptor Agonists, Inhibit Choroidal Neovascularization.
Article
3 sectionsContents
- Research
- See also
- References
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist that is selective to the alpha-2 adrenergic receptor. Guanabenz is used as an antihypertensive drug used in the treatment of high blood pressure (hypertension).
The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
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