IER3
Sign in to saveAlso known as DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1, immediate early response 3
Radiation-inducible immediate-early gene IEX-1 is a protein that in humans is encoded by the IER3 gene.
In the Vinony graph
Within Vinony's link graph, IER3 is referenced by 4 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Its subject is documented across 5 Wikipedia language editions.
Gene data
IER3- Name
- immediate early response 3
- Type
- protein-coding
- Position
- 30,743,199–30,744,555 (−)
- Aliases
- DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1
- Ensembl
- ENSG00000227231
- RefSeq RNA
- NM_003897.4, NM_052815.1
- RefSeq protein
- NP_003888.2
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
immediate early response 3
- Symbol
- IER3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:30,743,199-30,744,555
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 2894
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8870
- chromosome
- human chromosome 6
- genomic start
- 30710976
- genomic end
- 30744548
- cytogenetic location
- 6p21.33
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Radiation-inducible immediate-early gene IEX-1 is a protein that in humans is encoded by the IER3 gene.
This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.
Excerpted from Wikipedia’s “IER3” article, available under the CC BY-SA 4.0 licence.