IFNAR2

Name

interferon alpha and beta receptor subunit 2

Type

protein-coding

Position

33,205,282–33,265,675 (+)

Aliases

IFN-R, IFN-R-2, IFN-alpha-REC, IFNABR, IFNARB, IMD45

Ensembl

ENSG00000159110

RefSeq RNA

NM_000874.5, NM_001289125.3, NM_001289126.2, NM_001289128.2, NM_001385054.1

RefSeq protein

NP_000865.2, NP_001276054.1, NP_001276055.1, NP_001276057.1, NP_001371983.1

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. [provided by RefSeq, Jul 2020].

via MyGene.info

Gene · Ensembl

interferon alpha and beta receptor subunit 2

Symbol

IFNAR2

Biotype

Protein coding

Organism

Homo sapiens

Location

21:33,205,282-33,265,675

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein IFNAR2 PDB 1n6u.png

via Wikidata · CC0