IL2RG
Sign in to saveAlso known as CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1, interleukin 2 receptor subunit gamma
protein-coding gene in the species Homo sapiens
Gene data
IL2RG- Name
- interleukin 2 receptor subunit gamma
- Type
- protein-coding
- Chromosome
- X
- Position
- 71,107,404–71,112,108 (−)
- Aliases
- CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1
- Ensembl
- ENSG00000147168
- RefSeq RNA
- NM_000206.3, NM_001438870.1
- RefSeq protein
- NP_000197.1, NP_001425799.1
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010].
Gene Ontology
Biological process
Molecular function
Pathways
Cytokine-cytokine receptor interaction - Homo sapiens (human)Viral protein interaction with cytokine and cytokine receptor - Homo sapiens (human)Endocytosis - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)JAK-STAT signaling pathway - Homo sapiens (human)Th1 and Th2 cell differentiation - Homo sapiens (human)Th17 cell differentiation - Homo sapiens (human)Measles - Homo sapiens (human)Human T-cell leukemia virus 1 infection - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
interleukin 2 receptor subunit gamma
- Symbol
- IL2RG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:71,107,404-71,112,108
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein IL2RG PDB 2b5i.png
Show 5 more facts
- HomoloGene ID
- 172
- exact match
- identifiers.org/ncbigene/3561
- genomic end
- 70331958
- genomic start
- 70327254
- cytogenetic location
- Xq13.1
Sources (7)
via Wikidata · CC0
Connections
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