IL2RG

Also known as CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1, interleukin 2 receptor subunit gamma

protein-coding gene in the species Homo sapiens

Gene data

IL2RG

Name: interleukin 2 receptor subunit gamma
Type: protein-coding
Chromosome: X
Position: 71,107,404–71,112,108 (−)
Aliases: CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1
Ensembl: ENSG00000147168
RefSeq RNA: NM_000206.3, NM_001438870.1
RefSeq protein: NP_000197.1, NP_001425799.1

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010].