INHBA
Sign in to saveAlso known as EDF, FRP, inhibin beta A, inhibin beta A subunit, inhibin subunit beta A
Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.
Gene data
INHBA- Name
- inhibin subunit beta A
- Type
- protein-coding
- Position
- 41,667,168–41,705,834 (−)
- Aliases
- EDF, FRP
- Ensembl
- ENSG00000122641
- RefSeq RNA
- NM_002192.4, XM_017012174.2, XM_047420335.1, XM_054358157.1, XM_054358158.1
- RefSeq protein
- NP_002183.1, XP_016867663.2, XP_047276291.1, XP_054214132.1, XP_054214133.1
This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients. [provided by RefSeq, Aug 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
inhibin subunit beta A
- Symbol
- INHBA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:41,667,168-41,705,834
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.
== Function ==
Excerpted from Wikipedia’s “INHBA” article, available under the CC BY-SA 4.0 licence.