LPAR2

Also known as EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2

Lysophosphatidic acid receptor 2 also known as LPA2 is a protein that in humans is encoded by the LPAR2 gene. LPA2 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Gene data

LPAR2

Name: lysophosphatidic acid receptor 2
Type: protein-coding
Aliases: EDG-4, EDG4, LPA-2, LPA2

This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

lysophosphatidic acid receptor 2

Symbol: LPAR2
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:19,623,639-19,628,930
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 3465
genomic start: 19623655
exact match: identifiers.org/ncbigene/9170
genomic end: 19739739
cytogenetic location: 19p13.11

Sources (3)

via Wikidata · CC0

~1 min read

Article

8 sections

Contents

Function
Interactions
Evolution
[[Sequence homology|Paralogues]]
See also
References
Further reading
External links

== Function == This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins.