LPAR2
Sign in to saveAlso known as EDG-4, EDG4, LPA-2, LPA2, lysophosphatidic acid receptor 2
Gen der Spezies Homo sapiens
Gene data
LPAR2- Name
- lysophosphatidic acid receptor 2
- Type
- protein-coding
- Position
- 19,623,639–19,628,930 (−)
- Aliases
- EDG-4, EDG4, LPA-2, LPA2
- Ensembl
- ENSG00000064547
- RefSeq RNA
- NM_001395660.1, NM_004720.7
- RefSeq protein
- NP_001382589.1
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
G protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwaypositive regulation of cytosolic calcium ion concentrationpositive regulation of cytosolic calcium ion concentration
Molecular function
Pathways
Rap1 signaling pathway - Homo sapiens (human)Phospholipase D signaling pathway - Homo sapiens (human)Neuroactive ligand-receptor interaction - Homo sapiens (human)PI3K-Akt signaling pathway - Homo sapiens (human)Regulation of actin cytoskeleton - Homo sapiens (human)Pathogenic Escherichia coli infection - Homo sapiens (human)Pathways in cancer - Homo sapiens (human)Signal TransductionSignaling by GPCRClass A/1 (Rhodopsin-like receptors)
via MyGene.info
Gene · Ensembl
lysophosphatidic acid receptor 2
- Symbol
- LPAR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:19,623,639-19,628,930
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 3465
- genomic start
- 19623655
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9170
- genomic end
- 19739739
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.11
Sources (3)
via Wikidata · CC0