meloxicam

Also known as Mobic®, UHAC-62XX, UNII-VG2QF83CGL, UNII-vg2qf83cgl, Méloxicam, Meloxicamum

In the Vinony graph

Within Vinony's link graph, meloxicam is referenced by 524 other articles, and connects out to non-steroidal anti-inflammatory drug, peptic ulcer disease and gastrointestinal tract.

It sits within the topics Benzothiazines, Carboxamides and Cat medications.

Its subject is documented across 40 Wikipedia language editions.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 459437267
Drug.image: Meloxicam2DACS.svg
Drug.image_class: skin-invert-image
Drug.width: 200
Drug.image2: Meloxicam-from-xtal-3D-bs-17.png
Drug.image_class2: bg-transparent
Drug.tradename: Mobic, Meloxidyl, others
Drug.MedlinePlus: a601242
Drug.DailyMedID: Meloxicam
Drug.pregnancy_AU: C
Drug.routes_of_administration: By mouth, intravenous
Drug.class: Nonsteroidal anti-inflammatory drug (NSAID)
Drug.ATC_prefix: M01
Drug.ATC_suffix: AC06
Drug.ATC_supplemental: ,
Drug.legal_AU: S4

via Wikipedia infobox

Chemical data

Formula: C14H13N3O4S2
Molecular weight: 351.4 g/mol
IUPAC name: 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
InChIKey: ZRVUJXDFFKFLMG-UHFFFAOYSA-N
XLogP: 3
Polar surface area: 136 Å²
H-bond donors: 2
H-bond acceptors: 7
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 2000
Admin. routes: oral, parenteral
Indications: pain, ankylosing spondylitis, rheumatic disease, rheumatoid arthritis

via ChEMBL · EBI

Wikidata facts

Subclass of: heterocyclic compound
Has part: carbon
Mass: 351.035
Has use: medication

Show 10 more facts

chemical formula: C₁₄H₁₃N₃O₄S₂
isomeric SMILES: CC1=CN=C(S1)/N=C(/C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O)\O
Commons category: Meloxicam
canonical SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
World Health Organisation international non-proprietary name: meloxicam
defined daily dose: 15
subject has role: non-steroidal anti-inflammatory drug
physically interacts with: Prostaglandin-endoperoxide synthase 2
legal status (medicine): boxed warning
significant drug interaction: tacrolimus

Sources (5)

via Wikidata · CC0

~13 min read

Encyclopedic overview

23 sections

Contents

Medical uses
Adverse effects
Cardiovascular
Gastrointestinal
Mechanism of action
Pharmacokinetics
Absorption
Distribution
Metabolism
Excretion
Research and development
Veterinary use
Use of meloxicam in cats
US policy vs EU policy
Dosage and safety margin
Additional studies
Pharmacokinetics
Legal status
United States
European Union
Other countries
See also
References

Meloxicam, sold under the brand name Mobic among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation in rheumatic diseases and osteoarthritis. It is taken by mouth or given by injection into a vein. It is recommended that it be used for as short a period as possible and at a low dose.

Common side effects include abdominal pain, dizziness, swelling, headache, and a rash. Serious side effects may include heart disease, stroke, kidney problems, and stomach ulcers. Use is not recommended in the third trimester of pregnancy. It blocks cyclooxygenase-2 (COX-2) more than it blocks cyclooxygenase-1 (COX-1). It is in the oxicam family of chemicals and is closely related to piroxicam.

Excerpted from Wikipedia’s “meloxicam” article, available under the CC BY-SA 4.0 licence.