متاکولین

Also known as methacholine bromide, Provocholine®, Acetyl-beta-methylcholine, Acetylmethylcholine, MCh, Methacholine

Methacholine (INN, USAN) (trade name Provocholine), also known as acetyl-β-methylcholine, is a synthetic choline ester that acts as a non-selective muscarinic receptor agonist in the parasympathetic nervous system.

Chemical data

Formula: C8H18NO2+
Molecular weight: 160.23 g/mol
IUPAC name: 2-acetyloxypropyl(trimethyl)azanium
SMILES: CC(C[N+](C)(C)C)OC(=O)C
InChIKey: NZWOPGCLSHLLPA-UHFFFAOYSA-N
XLogP: 0.6
Polar surface area: 26.3 Å²
H-bond donors: 0
H-bond acceptors: 2
Formal charge: 1

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1986
Admin. routes: topical
Indications: asthma

via ChEMBL · EBI

Wikidata facts

Mass: 160.134
Has use: medication

Show 2 more facts

canonical SMILES: CC(C[N+](C)(C)C)OC(=O)C
chemical formula: C₈H₁₈NO₂⁺

Sources (3)

via Wikidata · CC0

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via Wikidata sitelinks · CC0