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methdilazine

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EntityQ6665709· pop 11· linked from 418 articles

methdilazine

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Also known as methdilazine hydrochloride, Tacaryl®, Methdilazinum, Metodilazina

Methdilazine (Dilosyn, Tacaryl) is a first-generation antihistamine with anticholinergic properties of the phenothiazine class.

Chemical data

Formula
C18H20N2S
Molecular weight
296.4 g/mol
IUPAC name
10-[(1-methylpyrrolidin-3-yl)methyl]phenothiazine

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
1982
Admin. routes
oral
Indications
allergic disease

via ChEMBL · EBI

Wikidata facts

Mass
296.13472
Show 4 more facts
chemical formula
C₁₈H₂₀N₂S
canonical SMILES
CN1CCC(C1)CN2C3=CC=CC=C3SC4=CC=CC=C42
defined daily dose
16.0
Commons category
Methdilazine
Sources (3)

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~1 min read

Article

3 sections
Contents
  • Synthesis
  • See also
  • References

Methdilazine (Dilosyn, Tacaryl) is a first-generation antihistamine with anticholinergic properties of the phenothiazine class.

==Synthesis== thumb|center|700px|Methdilazine synthesis: R. F. Feldkamp and Y. H. Wu; Mead Johnson & Company; (1960).

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