MFAP2

Also known as MAGP, MAGP-1, MAGP1, microfibrillar associated protein 2, microfibril associated protein 2

Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene.

In the Vinony graph

Vinony's link graph records 5 inbound references to MFAP2, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 1.

Vinony links it to 6 Wikipedia language editions.

Gene data

MFAP2

Name: microfibril associated protein 2
Type: protein-coding
Position: 16,972,933–16,981,616 (−)
Aliases: MAGP, MAGP-1, MAGP1
Ensembl: ENSG00000117122
RefSeq RNA: NM_001135247.2, NM_001135248.2, NM_002403.4, NM_017459.3, XM_047421027.1
RefSeq protein: NP_001128719.1, NP_001128720.1, NP_002394.1, NP_059453.1, XP_047276983.1

Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

Gene Ontology

Biological process

embryonic eye morphogenesis embryonic eye morphogenesis post-embryonic eye morphogenesis positive regulation of cold-induced thermogenesis positive regulation of cold-induced thermogenesis

Molecular function

fibronectin binding extracellular matrix structural constituent protein binding fibrinogen binding

Cellular component

microfibril microfibril microfibril microfibril extracellular region extracellular region extracellular matrix non-collagenous component of interstitial matrix

Pathways

Extracellular matrix organization Extracellular matrix organization Elastic fibre formation Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres Canonical and non-canonical Notch signaling

via MyGene.info

Gene · Ensembl

microfibril associated protein 2

Symbol: MFAP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:16,972,933-16,981,616
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 1801
genomic start: 16974502
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/4237
genomic end: 16980632
chromosome: human chromosome 1
cytogenetic location: 1p36.13

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

2 sections

Contents

References
Further reading

Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene.

Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. This gene encodes two transcripts with two alternatively spliced 5' untranslated exons. These two transcripts contain the same eight coding exons, and therefore, encode the same protein.

Excerpted from Wikipedia’s “MFAP2” article, available under the CC BY-SA 4.0 licence.