NEO1
Sign in to saveAlso known as IGDCC2, NGN, NTN1R2, neogenin 1
Neogenin is a protein that in humans is encoded by the NEO1 gene.
In the Vinony graph
Within Vinony's link graph, NEO1 is referenced by 10 other articles, and connects out to Q180686, human chromosome 15 and Ensembl genome database project.
It is catalogued under topics including Genes on human chromosome 15 and Human proteins.
Its subject is documented across 6 Wikipedia language editions.
Gene data
NEO1- Name
- neogenin 1
- Type
- protein-coding
- Position
- 73,051,645–73,305,205 (+)
- Aliases
- IGDCC2, NGN, NTN1R2
- Ensembl
- ENSG00000067141
- RefSeq RNA
- NM_001172623.2, NM_001172624.2, NM_001419531.1, NM_002499.4, XM_011521628.3
- RefSeq protein
- NP_001166094.1, NP_001166095.1, NP_001406460.1, NP_002490.2, XP_011519930.1
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
neogenin 1
- Symbol
- NEO1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:73,051,645-73,305,205
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein NEO1 PDB 1x5f.png
Show 5 more facts
- HomoloGene ID
- 1870
- exact match
- identifiers.org/ncbigene/4756
- genomic end
- 73305205
- genomic start
- 73344051
- cytogenetic location
- 15q24.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Neogenin is a protein that in humans is encoded by the NEO1 gene.
== Interactions ==
Excerpted from Wikipedia’s “NEO1” article, available under the CC BY-SA 4.0 licence.