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NS-398

Structure via PubChem · Public domain (PubChem)

EntityQ6955228· pop 7· linked from 214 articles

Also known as N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide, NS398, NS 398

NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.

Chemical data

Formula
C13H18N2O5S
Molecular weight
314.36 g/mol
IUPAC name
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
SMILES
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
InChIKey
KTDZCOWXCWUPEO-UHFFFAOYSA-N
XLogP
2.9
Polar surface area
110 Ų
H-bond donors
1
H-bond acceptors
6
Formal charge
0

via PubChem

Drug data · ChEMBL

Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
314.094
Show 6 more facts
found in taxon
Plantago major
canonical SMILES
CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
subject has role
COX-2 inhibitor
chemical formula
C₁₃H₁₈N₂O₅S
physically interacts with
Prostaglandin-endoperoxide synthase 2
Commons category
NS-398
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • See also
  • References

NS-398 is a COX-2 inhibitor used in the study of the function of cyclooxygenases.

==See also== Celecoxib Tilmacoxib (JTE-522)

Excerpted from Wikipedia’s “NS-398” article, available under the CC BY-SA 4.0 licence.

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