Also known as OG, OIF, SLRR3A, osteoglycin
Osteoglycin (also called mimecan), encoded by the OGN gene, is a human protein.
Gene data
OGN- Name
- osteoglycin
- Type
- protein-coding
- Position
- 92,383,268–92,406,734 (−)
- Aliases
- OG, OIF, SLRR3A
- Ensembl
- ENSG00000291350
- RefSeq RNA
- NM_014057.5, NM_024416.4, NM_033014.4
- RefSeq protein
- NP_054776.1, NP_077727.3, NP_148935.1
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded protein induces ectopic bone formation in conjunction with transforming growth factor beta and may regulate osteoblast differentiation. High expression of the encoded protein may be associated with elevated heart left ventricular mass. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
osteoglycin
- Symbol
- OGN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:92,383,268-92,406,734
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8542
- exact match
- identifiers.org/ncbigene/4969
- genomic end
- 95166978
- genomic start
- 92383268
- cytogenetic location
- 9q22.31
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Osteoglycin (also called mimecan), encoded by the OGN gene, is a human protein.
This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small keratan sulfate proteoglycan which contains tandem leucine-rich repeats (LRR). The gene expresses three transcript variants.