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ozolinone
Sign in to saveOzolinone is a loop diuretic which was never marketed.
In the Vinony graph
Within Vinony's link graph, ozolinone is referenced by 74 other articles, and connects out to collecting duct system, etozoline and International Standard Book Number.
It sits within the topics 1-Piperidinyl compounds, Abandoned drugs and Carboxylic acids.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C11H16N2O3S
- Molecular weight
- 256.32 g/mol
- IUPAC name
- (2Z)-2-(3-methyl-4-oxo-5-piperidin-1-yl-1,3-thiazolidin-2-ylidene)acetic acid
- SMILES
- CN1/C(=C/C(=O)O)/SC(C1=O)N2CCCCC2
- InChIKey
- NQFBZYYUAFJYNS-FPLPWBNLSA-N
- XLogP
- -1.4
- Polar surface area
- 86.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
32 papers- [Diuretics].Pathologie-biologie · 1986
- Attenuation by d-ozolinone of l-ozolinone-induced diuresis in rats.European journal of pharmacology · 1984
- Mechanisms of ozolinone-induced renin release and diuresis.American journal of hypertension · 1993
- Clinical pharmacokinetics of some newer diuretics.Clinical pharmacokinetics · 1987
- Stereoselective renal effects of the loop diuretic ozolinone in the anesthetized dog.Naunyn-Schmiedeberg's archives of pharmacology · 1995
via PubMed
Wikidata facts
- Subclass of
- carboxylic acid
- Mass
- 256.088163372
Show 5 more facts
- Commons category
- Ozolinone
- isomeric SMILES
- CN1/C(=C/C(=O)O)/SC(C1=O)N2CCCCC2
- canonical SMILES
- CN1/C(=C/C(=O)O)/SC(C1=O)N2CCCCC2
- chemical formula
- C₁₁H₁₆N₂O₃S
- subject has role
- diuretic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Ozolinone is a loop diuretic which was never marketed.
It is an active metabolite of etozoline.
Excerpted from Wikipedia’s “ozolinone” article, available under the CC BY-SA 4.0 licence.
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