pinacidil
Also known as Pindac®, pinacidil anhydrous
Pinacidil is a cyanoguanidine drug that opens ATP-sensitive potassium channels producing peripheral vasodilatation of arterioles. It reduces blood pressure and peripheral resistance and produces fluid retention.
Chemical data
- Formula
- C13H19N5
- Molecular weight
- 245.32 g/mol
- IUPAC name
- 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1989
- Admin. routes
- oral
via ChEMBL · EBI
Research
1,548 papers~1 min read
Article
3 sectionsContents
- Synthesis
- References
- External links
Pinacidil is a cyanoguanidine drug that opens ATP-sensitive potassium channels producing peripheral vasodilatation of arterioles. It reduces blood pressure and peripheral resistance and produces fluid retention.
Pinacidil has been associated with development of hypertrichosis in 2 to 13% of patients.