RAP1B
Sign in to saveAlso known as K-REV, RAL1B, RAP1B, member of RAS oncogene family
Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene.
Gene data
RAP1B- Name
- RAP1B, member of RAS oncogene family
- Type
- protein-coding
- Position
- 68,610,410–68,671,901 (+)
- Aliases
- K-REV, RAL1B, THC11
- Ensembl
- ENSG00000127314
- RefSeq RNA
- NM_001010942.3, NM_001251917.2, NM_001251918.2, NM_001251921.2, NM_001251922.2
- RefSeq protein
- NP_001010942.1, NP_001238846.1, NP_001238847.1, NP_001238850.1, NP_001238851.1
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RAP1B, member of RAS oncogene family
- Symbol
- RAP1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:68,610,410-68,671,901
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- PDB 1c1y EBI.jpg
Show 5 more facts
- HomoloGene ID
- 68719
- exact match
- identifiers.org/ncbigene/5908
- genomic end
- 69054372
- genomic start
- 68610855
- cytogenetic location
- 12q15
Sources (4)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene.
==References==
Available in 7 languages
via Wikidata sitelinks · CC0