RAP1B
Sign in to saveAlso known as K-REV, RAL1B, RAP1B, member of RAS oncogene family
Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene.
In the Vinony graph
Within Vinony's link graph, RAP1B is referenced by 6 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 7 Wikipedia language editions.
Gene data
RAP1B- Name
- RAP1B, member of RAS oncogene family
- Type
- protein-coding
- Position
- 68,610,410–68,671,901 (+)
- Aliases
- K-REV, RAL1B, THC11
- Ensembl
- ENSG00000127314
- RefSeq RNA
- NM_001010942.3, NM_001251917.2, NM_001251918.2, NM_001251921.2, NM_001251922.2
- RefSeq protein
- NP_001010942.1, NP_001238846.1, NP_001238847.1, NP_001238850.1, NP_001238851.1
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RAP1B, member of RAS oncogene family
- Symbol
- RAP1B
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:68,610,410-68,671,901
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- PDB 1c1y EBI.jpg
Show 8 more facts
- HomoloGene ID
- 68719
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5908
- genomic end
- 69054372
- genomic start
- 68610855
- chromosome
- human chromosome 12
- cytogenetic location
- 12q15
- expressed in
- bone marrow
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the RAP1B gene.
==References==
Excerpted from Wikipedia’s “RAP1B” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0