RAPH1
Sign in to saveAlso known as ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Ras-associated and pleckstrin homology domains-containing protein 1 is a protein that in humans is encoded by the RAPH1 gene.
Gene data
RAPH1- Name
- Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
- Type
- protein-coding
- Aliases
- ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6
This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].
via MyGene.info
Gene · Ensembl
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
- Symbol
- RAPH1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:203,394,345-203,535,478
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 71030
- exact match
- identifiers.org/ncbigene/65059
- genomic end
- 203535335
- genomic start
- 204259068
- cytogenetic location
- 2q33.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Ras-associated and pleckstrin homology domains-containing protein 1 is a protein that in humans is encoded by the RAPH1 gene.
==References==