RAPH1

Also known as ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6, Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

Ras-associated and pleckstrin homology domains-containing protein 1 is a protein that in humans is encoded by the RAPH1 gene.

In the Vinony graph

Vinony's link graph records 2 inbound references to RAPH1, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 2.

Vinony links it to 5 Wikipedia language editions.

Gene data

RAPH1

Name: Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
Type: protein-coding
Position: 203,394,345–203,535,478 (−)
Aliases: ALS2CR18, ALS2CR9, LPD, PREL-2, PREL2, RMO1, RalGDS/AF-6
Ensembl: ENSG00000173166
RefSeq RNA: NM_001329728.2, NM_001439019.1, NM_001439024.1, NM_001439027.1, NM_001439030.1
RefSeq protein: NP_001316657.1, NP_001425948.1, NP_001425953.1, NP_001425956.1, NP_001425959.1

This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016].