RSPH10B2

Also known as radial spoke head 10 homolog B2

Radial spoke head 10 homolog B2 is a protein that in humans is encoded by the RSPH10B gene.

In the Vinony graph

Vinony's link graph records 56 inbound references to RSPH10B2, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 7.

Vinony links it to 5 Wikipedia language editions.

Gene data

RSPH10B2

Name: radial spoke head 10 homolog B2
Type: protein-coding
Position: 6,754,101–6,799,365 (+)
Ensembl: ENSG00000169402
RefSeq RNA: NM_001099697.2, XM_005249833.5, XM_006715766.3, XM_011515491.2, XM_011515493.2
RefSeq protein: NP_001093167.1, XP_005249890.1, XP_006715829.1, XP_011513793.1, XP_011513795.1

This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017].