SDK2
Sign in to saveAlso known as sidekick cell adhesion molecule 2
Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to SDK2, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Vinony links it to 6 Wikipedia language editions.
Gene data
SDK2- Name
- sidekick cell adhesion molecule 2
- Type
- protein-coding
- Position
- 73,334,384–73,645,257 (−)
- Ensembl
- ENSG00000069188
- RefSeq RNA
- NM_001144952.2, NM_019064.3, XM_011524914.3, XM_011524915.3, XM_011524916.4
- RefSeq protein
- NP_001138424.1, XP_011523216.1, XP_011523217.1, XP_011523218.1, XP_047292269.1
The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
sidekick cell adhesion molecule 2
- Symbol
- SDK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:73,334,384-73,645,257
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SDK2 PDB 1wf5.png
Show 9 more facts
- HomoloGene ID
- 10406
- genetic association
- panic disorder
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/54549
- genomic end
- 73644445
- genomic start
- 71330523
- chromosome
- human chromosome 17
- cytogenetic location
- 17q25.1
- expressed in
- lactiferous duct
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.
==Function== The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined.
Excerpted from Wikipedia’s “SDK2” article, available under the CC BY-SA 4.0 licence.