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GeneQ18041092· pop 6· linked from 4 articles

Also known as sidekick cell adhesion molecule 2

Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.

Gene data

SDK2
Name
sidekick cell adhesion molecule 2
Type
protein-coding

The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

sidekick cell adhesion molecule 2

Symbol
SDK2
Biotype
Protein coding
Organism
Homo sapiens
Location
17:73,334,384-73,645,257
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image
Protein SDK2 PDB 1wf5.png
Show 5 more facts
HomoloGene ID
10406
genomic end
73644445
genomic start
71330523
cytogenetic location
17q25.1
Sources (6)

via Wikidata · CC0

~1 min read

Article

3 sections
Contents
  • Function
  • References
  • Further reading

Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.

==Function== The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined.

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