DOK2

Name

docking protein 2

Type

protein-coding

Position

21,908,873–21,913,960 (−)

Aliases

p56DOK, p56dok-2

Ensembl

ENSG00000147443

RefSeq RNA

NM_001317800.2, NM_001401272.1, NM_003974.4, NM_201349.3

RefSeq protein

NP_001304729.1, NP_001388201.1, NP_003965.2, NP_958728.1

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008].