MAPKAPK2

Name

MAPK activated protein kinase 2

Type

protein-coding

Position

206,684,886–206,734,284 (+)

Aliases

MAPKAP-K2, MK-2, MK2

Ensembl

ENSG00000162889

RefSeq RNA

NM_004759.5, NM_032960.4, XM_005273353.4, XM_017002810.2, XM_047434418.1

RefSeq protein

NP_004750.1, NP_116584.2, XP_005273410.1, XP_016858299.1, XP_047290374.1

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

MAPK activated protein kinase 2

Symbol

MAPKAPK2

Biotype

Protein coding

Organism

Homo sapiens

Location

1:206,684,871-206,734,284

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein MAPKAPK2 PDB 1kwp.png

via Wikidata · CC0