selamectin

Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats. It is structurally related to ivermectin and milbemycin. Selamectin is not approved for human use.

Research

266 papers

Ivermectin, a potential anticancer drug derived from an antiparasitic drug.Pharmacological research · 2021
Selamectin increases cisplatin sensitivity by inhibiting cisplatin-resistant genes expression and autophagy in uveal melanoma.Biochemical and biophysical research communications · 2023
Repurposing Selamectin as an Antimicrobial Drug against Hospital-Acquired Staphylococcus aureus Infections.Microorganisms · 2023
Tradition and innovation: Selamectin plus sarolaner. A new tool to control endo- and ectoparasites of cats-Studies from North America and Japan.Veterinary parasitology · 2019
In rabbits with cheyletiellosis is topical selamectin or injectable ivermectin a more effective treatment?Veterinary evidence · 2022

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Wikidata facts

Mass: 769.4401118359999

Show 5 more facts

chemical formula: C₄₃H₆₃O₁₁
canonical SMILES: CC1CCC2(CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5=NO)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)O)OC)C)OC1C7CCCCC7
isomeric SMILES: C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4CO[C@H]5[C@@]4([C@@H](C=C(/C5=N/O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)C)O[C@@H]1C7CCCCC7
NCI Thesaurus ID: C75233
Commons category: Selamectin

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