Also known as SNO, SnoA, SnoI, SnoN, SKI-like proto-oncogene, SKI like proto-oncogene
Ski-like protein is a protein that in humans is encoded by the SKIL gene.
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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Ski-like protein is a protein that in humans is encoded by the SKIL gene.
==Interactions== SKIL interacts with SKI protein, Mothers against decapentaplegic homolog 3 and Mothers against decapentaplegic homolog 2.
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).