Also known as DTDP1, MST117, MSTP117, MSTP140, SMAP2, bA270C4A.1, bA37D8.1, dJ421D16.1
SPARC-related modular calcium-binding protein 2 is a protein that in humans is encoded by the SMOC2 gene.
This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
via MyGene.info
SPARC-related modular calcium-binding protein 2 is a protein that in humans is encoded by the SMOC2 gene.
==Clinical relevance== This gene has been shown mutated in clinical cases of major dental developmental defects.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).