spirapril

Also known as Renormax®, SCH-33844

Spirapril, sold under the brand name Renormax among others, is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors.

Research

147 papers

Spirapril. A preliminary review of its pharmacology and therapeutic efficacy in the treatment of hypertension.Drugs · 1995
Efficacy and safety of spirapril in mild-to-moderate hypertension.Journal of cardiovascular pharmacology · 1999
Angiotensin-converting enzyme inhibitor induced cough compared with placebo, and other antihypertensives: A systematic review, and network meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2023
Comparison of efficacy of spirapril and enalapril in control of mild-to-moderate hypertension.Cardiovascular drugs and therapy · 1997
ACE inhibition in chronic renal failure and in the treatment of diabetic nephropathy: focus on spirapril.Journal of cardiovascular pharmacology · 1999

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Wikidata facts

Mass: 466.16

Show 5 more facts

chemical formula: C₂₂H₃₀N₂O₅S₂
canonical SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3(CC2C(=O)O)SCCS3
isomeric SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3(C[C@H]2C(=O)O)SCCS3
defined daily dose: 6
Commons category: Spirapril

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Spirapril, sold under the brand name Renormax among others, is an ACE inhibitor antihypertensive drug used to treat hypertension. It belongs to dicarboxy group of ACE inhibitors.

It was patented in 1980 and approved for medical use in 1995.