ACE inhibitor
Sign in to saveAlso known as Angiotensin converting enzyme inhibitor, ACE inhibitors, Angiotensin-converting enzyme inhibitor, Angiotensin-converting enzyme inhibitors, Acei, Angiotensin converting enzyme inhibitors
pharmaceutical drug used primarily for the treatment of hypertension (elevated blood pressure) and congestive heart failure
In the Vinony graph
Vinony's link graph records 611 inbound references to ACE inhibitor, and connects out to angiotensins, congenital disorder and amlodipine/valsartan.
It is catalogued under the topic ACE inhibitors.
Vinony links it to 40 Wikipedia language editions.
Key facts
- Use
- Hypertension
- Atc code
- C09A
- Biological target
- Angiotensin-converting enzyme
- Drugs com
- Drug Classes
- Consumer reports
- Best Buy Drugs
- Webmd
- MedicineNet RxList
- Mesh
- D000806
via Wikipedia infobox
Research
63,971 papers- ACE-inhibitor-related angioedema.Ear, nose, & throat journal · 2015
- ACE inhibitor-induced cough.DICP : the annals of pharmacotherapy · 1990
- [ACE-inhibitor induced angioedema].Laryngo- rhino- otologie · 2007
- ACE inhibitor induced intestinal angioedema.ANZ journal of surgery · 2022
- ACE inhibitor-induced cough and bronchospasm. Incidence, mechanisms and management.Drug safety · 1996
via PubMed
Wikidata facts
- Instance of
- drug class
- Subclass of
- protease inhibitor
Show 3 more facts
- Commons category
- ACE inhibitors
- topic's main category
- Category:ACE inhibitors
- different from
- acetylcholinesterase inhibitor
via Wikidata · CC0
~25 min read
Encyclopedic overview
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. This class of medicine works by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart.
ACE inhibitors inhibit the activity of angiotensin-converting enzyme, an important component of the renin–angiotensin system which converts angiotensin I to angiotensin II, and hydrolyses bradykinin. Therefore, ACE inhibitors decrease the formation of angiotensin II, a vasoconstrictor, and increase the level of bradykinin, a peptide vasodilator. This combination is synergistic in lowering blood pressure.
Excerpted from Wikipedia’s “ACE inhibitor” article, available under the CC BY-SA 4.0 licence.