Structure via PubChem · Public domain (PubChem)
supofen
Sign in to saveAlso known as Profenal®, R-25061, (+-)-2-(p-(2-thenoyl)phenyl)propionic acid, alpha-methyl-4-(2-thienylcarbonyl)benzeneacetic acid, p-2-thenoylhydratropic acid, 2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid, Suprofène, Suprofene
Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica that was marketed as 1% eye drops under the trade name Profenal.
Chemical data
- Formula
- C14H12O3S
- Molecular weight
- 260.31 g/mol
- IUPAC name
- 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
- SMILES
- CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O
- InChIKey
- MDKGKXOCJGEUJW-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 82.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- topical
- Indications
- rheumatic disease
via ChEMBL · EBI
Research
320 papers- Suprofen. A review of its pharmacodynamic and pharmacokinetic properties, and analgesic efficacy.Drugs · 1985
- Introduction to the pharmacology of suprofen.Pharmacology · 1983
- Suprofen.The Medical letter on drugs and therapeutics · 1986
- Suprofen: the pharmacology and clinical efficacy of a new non-narcotic peripheral analgesic.Clinics in rheumatic diseases · 1984
- Suprofen, a new peripheral analgesic.The Journal of pharmacology and experimental therapeutics · 1980
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 260.050715
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₄H₁₂O₃S
- canonical SMILES
- CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O
- World Health Organisation international non-proprietary name
- suprofen
- defined daily dose
- 0.4
- physically interacts with
- Prostaglandin-endoperoxide synthase 2
- Commons category
- Suprofen
Sources (3)
via Wikidata · CC0