tafluprost
Sign in to saveAlso known as AFP-168, MK-2452, Taflotan®, Tafluprosttrade
Tafluprost (trade names Taflotan by Santen Pharmaceutical, Zioptan by Merck in the US and Saflutan by Mundipharma in Australia) is a prostaglandin analogue. It is used topically (as eye drops) to control the progression of open-angle glaucoma and in the management of ocular hypertension, alone or in combination with other medication. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.
Wikidata facts
- Subclass of
- prostaglandins
- Mass
- 452.237
- Has use
- medication
Show 6 more facts
- Commons category
- Tafluprost
- chemical formula
- C₂₅H₃₄F₂O₅
- isomeric SMILES
- CC(C)OC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/C(COC2=CC=CC=C2)(F)F)O)O
- canonical SMILES
- CC(C)OC(=O)CCCC=CCC1C(CC(C1C=CC(COC2=CC=CC=C2)(F)F)O)O
- World Health Organisation international non-proprietary name
- tafluprost
- medical condition treated
- glaucoma
via Wikidata · CC0
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Encyclopedic overview
6 sectionsContents
- Adverse effects
- Interactions
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- References
{{Drugbox | IUPAC_name = Isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoate | image = Tafluprost_structure.svg | image_class = skin-invert-image
| tradename = Saflutan, Taflotan, Zioptan | Drugs.com = | pregnancy_AU = | pregnancy_category = | legal_AU = | legal_CA = Rx-only | legal_CA_comment = | legal_UK = | legal_US = Rx-only | legal_status = | routes_of_administration = Topical eye drops
Excerpted from Wikipedia’s “tafluprost” article, available under the CC BY-SA 4.0 licence.
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