TNFRSF6B

Also known as DCR3, DJ583P15.1.1, M68, M68E, TR6, tumor necrosis factor receptor superfamily member 6b, TNF receptor superfamily member 6b

protein-coding gene in the species Homo sapiens

Gene data

TNFRSF6B

Name: TNF receptor superfamily member 6b
Type: protein-coding
Position: 63,696,368–63,698,689 (+)
Aliases: DCR3, DJ583P15.1.1, M68, M68E, TR6
Ensembl: ENSG00000243509
RefSeq RNA: NM_003823.4, NM_032945.2
RefSeq protein: NP_003814.1

This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011].