UFM1

Also known as BM-002, C13orf20, ubiquitin-fold modifier 1, ubiquitin fold modifier 1, HLD14

Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene.

In the Vinony graph

Vinony's link graph records 110 inbound references to UFM1, and connects out to PubMed, human chromosome 13 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 13.

Vinony links it to 5 Wikipedia language editions.

Gene data

UFM1

Name: ubiquitin fold modifier 1
Type: protein-coding
Position: 38,349,528–38,363,619 (+)
Aliases: BM-002, C13orf20, HLD14
Ensembl: ENSG00000120686
RefSeq RNA: NM_001286703.2, NM_001286704.2, NM_001286705.2, NM_001286706.2, NM_016617.4
RefSeq protein: NP_001273632.1, NP_001273633.1, NP_001273634.1, NP_001273635.1, NP_057701.1

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM 610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM 603173) (Komatsu et al., 2004 [PubMed 15071506]).[supplied by OMIM, Dec 2008].

Gene Ontology

Biological process

brain development regulation of intracellular estrogen receptor signaling pathway response to endoplasmic reticulum stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress negative regulation of protein import into nucleus negative regulation of apoptotic process

Molecular function

protein binding

Cellular component

nucleus nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm cytoplasm

via MyGene.info

Gene · Ensembl

ubiquitin fold modifier 1

Symbol: UFM1
Biotype: Protein coding
Organism: Homo sapiens
Location: 13:38,349,528-38,363,619
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein UFM1 PDB 1j0g.png

Show 8 more facts

HomoloGene ID: 9594
exact match: identifiers.org/ncbigene/51569
found in taxon: Homo sapiens
genomic end: 38937140
genomic start: 38923986
chromosome: human chromosome 13
cytogenetic location: 13q13.3
expressed in: sperm

Sources (5)

via Wikidata · CC0

~2 min read

Encyclopedic overview

4 sections

Contents

Function
References
Further reading
External links

Ubiquitin-fold modifier 1, also known as UFM1, is a protein which in humans is encoded by the UFM1 gene.

UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 and E2-like conjugating enzyme UFC1. This process is often referred to as UFMylation.

Excerpted from Wikipedia’s “UFM1” article, available under the CC BY-SA 4.0 licence.