วาลาไซโคลเวียร์

Also known as 256U87 HCl, valacyclovir hydrochloride (monohydrate), Valtrex®, Zelitrex®, L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester, L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine, Valaciclovirum, Valacyclovir

Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. It is taken by mouth.

Key facts

Drug.KEGG: D08664
Drug.Verifiedfields: changed
Drug.verifiedrevid: 470627698
Drug.image: Valaciclovir structure.svg
Drug.image_class: skin-invert-image
Drug.USAN: valacyclovir hydrochloride
Drug.tradename: Valtrex, Zelitrex, others
Drug.MedlinePlus: a695010
Drug.DailyMedID: Valacyclovir
Drug.pregnancy_AU: B3
Drug.routes_of_administration: By mouth
Drug.class: Antiviral
Drug.ATC_prefix: J05
Drug.ATC_suffix: AB11
Drug.legal_AU: S4
Drug.legal_UK: POM
Drug.legal_US: Rx-only
Drug.legal_status: Rx-only

via Wikipedia infobox

Chemical data

Formula: C13H20N6O4
Molecular weight: 324.34 g/mol
IUPAC name: 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
SMILES: CC(C)[C@@H](C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)N
InChIKey: HDOVUKNUBWVHOX-QMMMGPOBSA-N
XLogP: -0.9
Polar surface area: 147 Å²
H-bond donors: 3
H-bond acceptors: 7
Formal charge: 0

via PubChem

Research

2,018 papers

via PubMed

Wikidata facts

Subclass of: nucleoside analogue
Mass: 324.155
Has use: medication

Show 10 more facts

chemical formula: C₁₃H₂₀N₆O₄
route of administration: oral administration
Commons category: Valaciclovir
canonical SMILES: CC(C)C(C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N
isomeric SMILES: CC(C)[C@@H](C(=O)OCCOCN1C=NC2=C1NC(=NC2=O)N)N
medical condition treated: ophthalmic zoster
defined daily dose: 3
subject has role: antiviral drug
stylized name: valACYclovir
significant drug interaction: foscarnet

Sources (6)

via Wikidata · CC0

Gallery (5)

Available in 27 languages

Show 8 more

via Wikidata sitelinks · CC0