AURKA
Sign in to saveAlso known as AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6
protein-coding gene in the species Homo sapiens
Gene data
AURKA- Name
- aurora kinase A
- Type
- protein-coding
- Position
- 56,369,382–56,392,566 (−)
- Aliases
- AIK, ARK1, AURA, BTAK, PPP1R47, STK15, STK6, STK7
- Ensembl
- ENSG00000087586
- RefSeq RNA
- NM_001323303.2, NM_001323304.2, NM_001323305.2, NM_001424417.1, NM_001424418.1
- RefSeq protein
- NP_001310232.1, NP_001310233.1, NP_001310234.1, NP_001411346.1, NP_001411347.1
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
aurora kinase A
- Symbol
- AURKA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:56,369,382-56,392,566
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein AURKA PDB 1mq4.png
Show 6 more facts
- HomoloGene ID
- 2670
- exact match
- identifiers.org/ncbigene/6790
- genomic end
- 54967393
- genomic start
- 54944445
- cytogenetic location
- 20q13.2
- Commons category
- Aurora kinase A
via Wikidata · CC0