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GeneQ18045470· pop 7· linked from 117 articles

Also known as BEHAB, CSPG7, Brevican

Brevican core protein is a protein that in humans is encoded by the BCAN gene. Brevican is a member of the lectican protein family.

Gene data

BCAN
Name
brevican
Type
protein-coding
Aliases
BEHAB, CSPG7

This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in gliomas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].

via MyGene.info

Gene · Ensembl

brevican

Symbol
BCAN
Biotype
Protein coding
Organism
Homo sapiens
Location
1:156,641,390-156,659,532
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
7244
genomic start
156611182
genomic end
156629324
cytogenetic location
1q23.1
Sources (4)

via Wikidata · CC0

~1 min read

Article

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Contents
  • References
  • Further reading
  • External links

Brevican core protein is a protein that in humans is encoded by the BCAN gene. Brevican is a member of the lectican protein family.

Brevican is localised to the surface of neurons in the brain. In melanocytic cells, BCAN gene expression may be regulated by MITF.

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