Also known as beta chemokine exodus-2, SLC, 6Ckine, secondary lymphoid tissue chemokine, C-C motif chemokine 21, Efficient Chemoattractant for Lymphocytes, Secondary lymphoid-tissue chemokine, CCL21
Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC). CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7. The main function of CCL21 is to guide CCR7 expressing leukocytes to the secondary lymphoid organs, such as lymph nodes and Peyer's patches.
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Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC). CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7. The main function of CCL21 is to guide CCR7 expressing leukocytes to the secondary lymphoid organs, such as lymph nodes and Peyer's patches.
== Gene == The gene for CCL21 is located on human chromosome 9. CCL21 is classified as a homeostatic chemokine, it is produced constitutively. However, its expression increases during inflammation.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).