C-C motif chemokine receptor 4

Also known as chemokine (C-C motif) receptor 4, C-C CKR-4, CCR-4, K5-5, CCR4, chemokine (C-C) receptor 4, C-C chemokine receptor type 4

C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also been designated CD194 (cluster of differentiation 194).

Clinical Trials

1 registered

PHASE2RECRUITING
Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic AdenocarcinomaGulam Manji · NCT04543071

via ClinicalTrials.gov

~1 min read

Article

4 sections

Contents

Clinical significance
As a drug target
References
External links

C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also been designated CD194 (cluster of differentiation 194).

The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines: CCL2 (MCP-1) CCL4 (MIP-1) CCL5 (RANTES) CCL17 (TARC) CCL22 (Macrophage-derived chemokine)