Gene data
C6- Name
- complement C6
- Type
- protein-coding
- Position
- 41,140,236–41,261,561 (−)
- Ensembl
- ENSG00000039537
- RefSeq RNA
- NM_000065.5, NM_001115131.4, XM_006714496.5, XM_011514114.4, XM_011514115.4
- RefSeq protein
- NP_000056.2, NP_001108603.2, XP_006714559.1, XP_011512416.1, XP_011512417.1
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012].
Gene Ontology
Biological process
Molecular function
Pathways
Complement and coagulation cascades - Homo sapiens (human)Prion disease - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)Systemic lupus erythematosus - Homo sapiens (human)Complement cascadeTerminal pathway of complementInnate Immune SystemImmune SystemRegulation of Complement cascadeAllograft Rejection
via MyGene.info
Gene · Ensembl
complement C6
- Symbol
- C6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:41,140,236-41,261,561
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- different from
- C6
- HomoloGene ID
- 47
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/729
- genomic end
- 41261540
- genomic start
- 41142116
- chromosome
- human chromosome 5
- cytogenetic location
- 5p13.1
via Wikidata · CC0