Also known as complement C6
protein-coding gene in the species Homo sapiens
Gene data
C6- Name
- complement C6
- Type
- protein-coding
- Position
- 41,140,236–41,261,561 (−)
- Ensembl
- ENSG00000039537
- RefSeq RNA
- NM_000065.5, NM_001115131.4, XM_006714496.5, XM_011514114.4, XM_011514115.4
- RefSeq protein
- NP_000056.2, NP_001108603.2, XP_006714559.1, XP_011512416.1, XP_011512417.1
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012].
Gene Ontology
Biological process
Molecular function
Pathways
Complement and coagulation cascades - Homo sapiens (human)Prion disease - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)Systemic lupus erythematosus - Homo sapiens (human)Complement cascadeTerminal pathway of complementInnate Immune SystemImmune SystemRegulation of Complement cascadeAllograft Rejection
via MyGene.info
Gene · Ensembl
complement C6
- Symbol
- C6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:41,140,236-41,261,561
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 47
- exact match
- identifiers.org/ncbigene/729
- genomic end
- 41261540
- genomic start
- 41142116
- cytogenetic location
- 5p13.1
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 5
Entity
Ensembl genome database project
Entity
protein
Entity
Wikidata
Entity
gene
Entity
chromosome
Entity
digital object identifier
Entity
inflammation
Entity
human genome
Entity
Q229883
Entity
base pair
Entity
locus
Entity
Medical Subject Headings
Entity
gene expression
Entity
complement system
Entity
Online Mendelian Inheritance in Man
Entity
Protein Data Bank
Entity
Q22908627
Entity
cytotoxicity
Entity