SIX1
Sign in to saveAlso known as BOS3, DFNA23, TIP39, SIX homeobox 1
protein-coding gene in the species Homo sapiens
Gene data
SIX1- Name
- SIX homeobox 1
- Type
- protein-coding
- Position
- 60,643,421–60,658,259 (−)
- Aliases
- BOS3, DFNA23, TIP39
- Ensembl
- ENSG00000126778
- RefSeq RNA
- NM_001425142.1, NM_005982.4
- RefSeq protein
- NP_001412071.1, NP_005973.1
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3). [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
transcription cis-regulatory region bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingRNA polymerase II cis-regulatory region sequence-specific DNA bindingDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specificDNA-binding transcription factor activity, RNA polymerase II-specifictranscription coactivator binding
Pathways
via MyGene.info
Gene · Ensembl
SIX homeobox 1
- Symbol
- SIX1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:60,643,421-60,658,259
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 4360
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6495
- genomic end
- 61124977
- genomic start
- 60643421
- chromosome
- human chromosome 14
- cytogenetic location
- 14q23.1
via Wikidata · CC0