CASP6

Name

caspase 6

Type

protein-coding

Position

109,688,622–109,703,583 (−)

Aliases

CSP-6, MCH2, caspase-6

Ensembl

ENSG00000138794

RefSeq RNA

NM_001226.4, NM_032992.3, NR_133012.2, XM_047416244.1, XM_047416245.1

RefSeq protein

NP_001217.2, NP_116787.1, XP_047272200.1, XP_047272201.1, XP_054206943.1

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015].

via MyGene.info

Gene · Ensembl

caspase 6

Symbol

CASP6

Biotype

Protein coding

Organism

Homo sapiens

Location

4:109,685,837-109,703,583

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein CASP6 PDB 1MI9.png

via Wikidata · CC0