CDC25C

Also known as CDC25, PPP1R60, cell division cycle 25C

M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.

Gene data

CDC25C

Name: cell division cycle 25C
Type: protein-coding
Aliases: CDC25, PPP1R60

This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015].

via MyGene.info

Gene · Ensembl

cell division cycle 25C

Symbol: CDC25C
Biotype: Protein coding
Organism: Homo sapiens
Location: 5:138,285,251-138,338,355
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein CDC25C PDB 3BZI.png

Show 5 more facts

HomoloGene ID: 1356
exact match: identifiers.org/ncbigene/995
genomic end: 137674044
genomic start: 137620954
cytogenetic location: 5q31.2

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M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene.

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.