cenegermin
Sign in to saveCenegermin, sold under the brand name Oxervate, also known as recombinant human nerve growth factor, is a recombinant form of human nerve growth factor. Cenegermin is a peripherally selective agonist of the tropomyosin receptor kinase A (TrkA) and low-affinity nerve growth factor receptor (p75NTR).
In the Vinony graph
Vinony's link graph records 355 inbound references to cenegermin, and connects out to World Health Organization, digital object identifier and chemical formula.
Vinony files it under Chemicals that do not have a ChemSpider ID assigned, Drugs with non-standard legal status and Infobox drug articles without a structure image.
Vinony links it to 9 Wikipedia language editions.
Clinical Trials
10 registered- COMPLETEDNerve Growth Factor for the Treatment of Cornea DiseaseStanford University · NCT04552730
- PHASE4COMPLETEDStudy to Evaluate OXERVATE® in Patients With Stage 1 Neurotrophic KeratitisDompé Farmaceutici S.p.A · NCT04485546
- COMPLETEDCorneal Nerves After Treatment With CenegerminUniversity of California, Los Angeles · NCT04627571
- PHASE3RECRUITINGAn Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCEDDompé Farmaceutici S.p.A · NCT07519902
- PHASE4ACTIVE_NOT_RECRUITINGDOMPE -MT Neurotrophic KeratitisToyos Clinic · NCT06947850
- PHASE3NOT_YET_RECRUITINGEfficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)Dompé Farmaceutici S.p.A · NCT07453888
~1 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Society and culture
- Names
- References
- Further reading
Cenegermin, sold under the brand name Oxervate, also known as recombinant human nerve growth factor, is a recombinant form of human nerve growth factor. Cenegermin is a peripherally selective agonist of the tropomyosin receptor kinase A (TrkA) and low-affinity nerve growth factor receptor (p75NTR).
The most common side effects include eye pain and inflammation, increased lacrimation (watery eyes), pain in the eyelid and sensation of a foreign body in the eye.
Excerpted from Wikipedia’s “cenegermin” article, available under the CC BY-SA 4.0 licence.