cevimeline
Sign in to saveAlso known as Cevimelina, 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Sni 2011, Cevimelinum, Evoxac
Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren's disease.
Research
231 papers- Cevimeline.2012
- Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.International journal of molecular sciences · 2021
- Cevimeline.Drugs · 2008
- EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.Annals of the rheumatic diseases · 2020
- Xerostomia of Various Etiologies: A Review of the Literature.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2016
via PubMed
Wikidata facts
- Mass
- 199.103085
Show 4 more facts
- chemical formula
- C₁₀H₁₇NOS
- canonical SMILES
- CC1OC2(CN3CCC2CC3)CS1
- defined daily dose
- 90
- Commons category
- Cevimeline
Sources (3)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Medical uses
- Side effects
- Mechanism of action
- See also
- References
- External links
Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren's disease.
== Medical uses == Cevimeline is used in the treatment of xerostomia (dry mouth) and Sjögren's syndrome. It increases the production of saliva.
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