Structure via PubChem · Public domain (PubChem)
cevimelina
Sign in to saveAlso known as 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine, Sni 2011, Cevimelinum, Evoxac
farmaco
Chemical data
- Formula
- C10H17NOS
- Molecular weight
- 199.32 g/mol
- IUPAC name
- 2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]
- SMILES
- CC1OC2(CN3CCC2CC3)CS1
- InChIKey
- WUTYZMFRCNBCHQ-UHFFFAOYSA-N
- XLogP
- 1.5
- Polar surface area
- 37.8 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2000
- Admin. routes
- oral
- Indications
- xerostomia
via ChEMBL · EBI
Research
231 papers- Cevimeline.2012
- Neuropharmacology of Cevimeline and Muscarinic Drugs-Focus on Cognition and Neurodegeneration.International journal of molecular sciences · 2021
- Cevimeline.Drugs · 2008
- EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.Annals of the rheumatic diseases · 2020
- Xerostomia of Various Etiologies: A Review of the Literature.Advances in clinical and experimental medicine : official organ Wroclaw Medical University · 2016
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 199.103085
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₀H₁₇NOS
- subject has role
- muscarinic agonist
- canonical SMILES
- CC1OC2(CN3CCC2CC3)CS1
- defined daily dose
- 90
- medical condition treated
- Sjögren's syndrome
- Commons category
- Cevimeline
Sources (3)
via Wikidata · CC0
Article · Italiano
La cevimelina è un farmaco parasimpaticomimetico e , con particolare selettività verso i recettori muscarinici M3. Nel 2000 è stato approvato dalla Food and Drug Administration per il trattamento della xerostomia nei pazienti affetti da sindrome di Sjögren.
Abstract from DBpedia / Wikipedia · CC BY-SA