CIRBP
Sign in to saveAlso known as CIRP, cold inducible RNA binding protein
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia. It is thought to be involved in DNA repair.
In the Vinony graph
Within Vinony's link graph, CIRBP is referenced by 5 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 9 Wikipedia language editions.
Gene data
CIRBP- Name
- cold inducible RNA binding protein
- Type
- protein-coding
- Position
- 1,259,384–1,274,880 (+)
- Aliases
- CIRP
- Ensembl
- ENSG00000099622
- RefSeq RNA
- NM_001280.3, NM_001300815.2, NM_001300829.2, NM_001437523.1, NM_001437524.1
- RefSeq protein
- NP_001271.1, NP_001287744.1, NP_001287758.1, NP_001424452.1, NP_001424453.1
Enables mRNA 3'-UTR binding activity and small ribosomal subunit rRNA binding activity. Involved in mRNA stabilization; positive regulation of translation; and response to UV. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
cold inducible RNA binding protein
- Symbol
- CIRBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:1,259,384-1,274,880
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CIRBP PDB 1x5s.png
Show 8 more facts
- HomoloGene ID
- 980
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1153
- genomic end
- 1274879
- genomic start
- 1259384
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.3
- Commons category
- Cold-inducible RNA-binding protein
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene. The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia. It is thought to be involved in DNA repair.
== References ==
Excerpted from Wikipedia’s “CIRBP” article, available under the CC BY-SA 4.0 licence.