Structure via PubChem · Public domain (PubChem)
คอเลสติพอล
Sign in to saveAlso known as Epichlorohydrin-tetraethylenepentamine polymer, Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane, Colestipolum
Colestipol (trade names Colestid, Cholestabyl) is a bile acid sequestrant used to lower blood cholesterol, specifically low-density lipoprotein (LDL). It is also used to reduce stool volume and frequency, and in the treatment of chronic diarrhea.
In the Vinony graph
Vinony's link graph records 106 inbound references to คอเลสติพอล, and connects out to colestyramine, liver and International Standard Book Number.
Vinony files it under Bile acid sequestrants, Chemicals that do not have a ChemSpider ID assigned and Drugboxes which contain changes to verified fields.
Vinony links it to 16 Wikipedia language editions.
Chemical data
- Formula
- C11H28ClN5O
- Molecular weight
- 281.83 g/mol
- IUPAC name
- N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine;2-(chloromethyl)oxirane
- SMILES
- C1C(O1)CCl.C(CNCCNCCNCCN)N
- InChIKey
- GMRWGQCZJGVHKL-UHFFFAOYSA-N
- Polar surface area
- 101 Ų
- H-bond donors
- 5
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Unknown
via ChEMBL · EBI
Research
568 papers- Colestipol.2006
- Colestipol.2012
- Colestipol.2026
- Colestipol: a review of its pharmacological properties and therapeutic efficacy in patients with hypercholesterolaemia.Drugs · 1980
- Colestipol and probucol: treatment of primary and familial hypercholesterolemia and amelioration of atherosclerosis.Annals of internal medicine · 1982
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 281.198238
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₁H₂₈ClN₅O
- canonical SMILES
- C1C(O1)CCl.C(CNCCNCCNCCN)N
- defined daily dose
- 20
- NCI Thesaurus ID
- C81540
Sources (3)
via Wikidata · CC0
Gallery (4)
Available in 16 languages
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via Wikidata sitelinks · CC0