cyproterone
Sign in to saveAlso known as Gen-Cyproterone, CyPat, Ciproterone, SH-80881
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use. It is a precursor of cyproterone acetate (CPA), an antiandrogen, progestin, and antigonadotropin which was introduced instead of cyproterone and is widely used as a medication. Cyproterone and CPA were among the first antiandrogens to be developed.
Research
3,849 papers- Cyproterone. A review of its pharmacology and therapeutic efficacy in prostate cancer.Drugs & aging · 1994
- Cyproterone and hypersexuality.The New Zealand medical journal · 1977
- Cyproterone acetate.Lancet (London, England) · 1976
- Cyproterone acetate.Lancet (London, England) · 1976
- Cyproterone-induced hepatotoxicity.The Annals of pharmacotherapy · 1995
via PubMed
Wikidata facts
- Mass
- 374.165
Show 5 more facts
- chemical formula
- C₂₂H₂₇ClO₃
- canonical SMILES
- CC(=O)C1(CCC2C1(CCC3C2C=C(C4=CC(=O)C5CC5C34C)Cl)C)O
- isomeric SMILES
- CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)[C@@H]5C[C@@H]5[C@]34C)Cl)C)O
- World Health Organisation international non-proprietary name
- cyproterone
- Commons category
- Cyproterone
via Wikidata · CC0
~6 min read
Article
11 sectionsContents
- Pharmacology
- Pharmacodynamics
- Antiandrogenic activity
- Other activities
- Chemistry
- History
- Society and culture
- Generic names
- Research
- References
- Further reading
Cyproterone, also known by its developmental code name SH-80881, is a steroidal antiandrogen which was studied in the 1960s and 1970s but was never introduced for medical use. It is a precursor of cyproterone acetate (CPA), an antiandrogen, progestin, and antigonadotropin which was introduced instead of cyproterone and is widely used as a medication. Cyproterone and CPA were among the first antiandrogens to be developed.
The term cyproterone is often used as a synonym and shorthand for cyproterone acetate, and when the term occurs, what is almost always being referred to is, confusingly, CPA and not actually cyproterone. Cyproterone itself, unlike CPA, was never introduced for medical use and hence is not available as a medication.